implications for the immunotherapy of cancer

Background: Interleukin-15 (IL-15) is an important cytokine necessary for proliferation and maintenance of natural killer (NK) and CD8+ T cells, and with great promise as an immuno-oncology therapeutic. However, IL-15 has a very short half-life and a single administration does not provide the sustained exposure required for optimal stimulation of target immune cells. The purpose of this…

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kidney releases a non-polymerizing form of Uromodulin in the urine and circulation that retains the external hydrophobic patch

Processing of mature urinary THP, which polymerizes into supra-molecular filaments, requires cleavage of an external hydrophobic patch (EHP) at the C-terminus. However, THP in the circulation is not polymerized, and it remains unclear if non-aggregated forms of THP exist natively in the urine. We propose that an alternative processing path, which retains the EHP domain, can lead…

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Lipid Peroxidation

Lipid Peroxidation (MDA) Assay Bundle (Colorimetric/Fluorometric) 

Related merchandise Evaluation the oxidative stress marker and assay info, or the whole metabolism assay info to check additional assays for metabolites, metabolic enzymes, mitochondrial function, and oxidative stress, and as well as how one can assay metabolic function in dwell cells using your plate reader. Moreover see the favored 4-HNE Assay Bundle ab238538 instead marker of lipid peroxidation and…

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